| Araceae | Philodendron leyvae García-Barr. | Vulnerable | Endemic |
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| Asteraceae | Achyrocline mollis Benth. | Critically Endangered | Native |
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| Asteraceae | Ageratina latipes (Benth.) R.M.King & H.Rob. | Near Threatened | Endemic |
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| Asteraceae | Espeletia barclayana Cuatrec. | Near Threatened | Endemic |
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| Asteraceae | Espeletia cabrerensis Cuatrec. | Vulnerable | Endemic |
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| Asteraceae | Espeletia cayetana (Cuatrec.) Cuatrec. | Endangered | Endemic |
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| Asteraceae | Espeletia chocontana Cuatrec. | Endangered | Endemic |
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| Asteraceae | Espeletia miradorensis (Cuatrec.) Cuatrec. | Critically Endangered | Endemic |
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| Asteraceae | Espeletia summapacis Cuatrec. | Endangered | Endemic |
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| Asteraceae | Gynoxys hirsuta Wedd. | Vulnerable | Endemic |
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| Asteraceae | Gynoxys hirsutissima Cuatrec. | Critically Endangered | Endemic |
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| Begoniaceae | Begonia tropaeolifolia A.DC. | Endangered | Native |
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| Berberidaceae | Berberis carupensis L.A.Camargo | Critically Endangered | Endemic |
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| Berberidaceae | Berberis sumapazana L.A.Camargo | Endangered | Endemic |
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| Berberidaceae | Berberis tabiensis L.A.Camargo | Vulnerable | Endemic |
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| Berberidaceae | Berberis uribei L.A.Camargo | Critically Endangered | Endemic |
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| Bignoniaceae | Handroanthus chrysanthus (Jacq.) S.O.Grose | Vulnerable | Native | cultivated |
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| Bromeliaceae | Pitcairnia petraea L.B.Sm. | Endangered | Endemic |
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| Bromeliaceae | Tillandsia breviturneri Betancur & Néstor García | Endangered | Endemic |
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| Bromeliaceae | Tillandsia chartacea L.B.Sm. | Critically Endangered | Endemic |
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| Bromeliaceae | Tillandsia fusiformis L.B.Sm. | Endangered | Native |
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| Brunelliaceae | Brunellia racemifera Tul. | Endangered | Endemic |
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| Caprifoliaceae | Valeriana secunda B.Eriksen | Endangered | Native |
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| Clethraceae | Clethra rugosa Steyerm. | Vulnerable | Native |
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| Clusiaceae | Clusia cundinamarcensis Cuatrec. | Vulnerable | Endemic |
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| Cunoniaceae | Weinmannia karsteniana Szyszyl. | Near Threatened | Native |
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| Dryopteridaceae | Elaphoglossum sodiroi (Baker) Christ | Critically Endangered | Native |
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| Ericaceae | Gaultheria santanderensis A.C.Sm. | Near Threatened | Endemic |
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| Ericaceae | Plutarchia guascensis (Cuatrec.) A.C.Sm. | Vulnerable | Endemic |
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| Fabaceae | Lupinus colombiensis C.P.Sm. | Vulnerable | Endemic |
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| Lamiaceae | Salvia cocuyana Fern.Alonso | Endangered | Endemic |
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| Melastomataceae | Meriania mutabilis (Gleason) Humberto Mend. & Fern.Alonso | Vulnerable | Endemic |
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| Melastomataceae | Meriania mutisii (Bonpl.) Humberto Mend. & Fern.Alonso | Near Threatened | Endemic |
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| Melastomataceae | Miconia annulata (Naudin) Triana | Vulnerable | Endemic |
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| Melastomataceae | Miconia miocarpa Naudin | Endangered | Endemic |
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| Melastomataceae | Miconia parvifolia Cogn. | Vulnerable | Endemic |
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| Melastomataceae | Miconia reclinata (Bonpl.) Naudin | Vulnerable | Endemic |
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| Orchidaceae | Masdevallia racemosa Lindl. | Vulnerable | Endemic |
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| Plantaginaceae | Aragoa corrugatifolia Fern.Alonso | Vulnerable | Endemic |
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| Plantaginaceae | Aragoa cupressina H.B. & K. | Endangered | Endemic |
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| Plantaginaceae | Aragoa perez-arbelaeziana Romero | Endangered | Endemic |
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| Primulaceae | Ardisia sapida Cuatrec. | Near Threatened | Endemic |
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| Sapindaceae | Allophylus goudotii (Triana & Planch.) Radlk. | Near Threatened | Endemic |
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| Viburnaceae | Viburnum subsessile Killip & A.C.Sm. | Endangered | Endemic |
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| Viburnaceae | Viburnum suratense Killip & A.C.Sm. | Endangered | Endemic |
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