1,3 - Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA 0015 and their antibacterial activity Author Kumla, Decha * & ICBAS-Instituto de Ciˆencias Biom´edicas Abel Salazar, Rua de Jorge Viterbo Ferreira, 228, 4050 - 313, Porto, Portugal & * & Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leix ˜ oes, Av. General Norton de Matos s / n, 4450 - 208, Matosinhos, Portugal Author Sousa, Emilia * & Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leix ˜ oes, Av. General Norton de Matos s / n, 4450 - 208, Matosinhos, Portugal & Laborat´orio de Química Orgˆanica, Departamento de Ciˆencias Químicas, Faculdade de Farm´acia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050 - 313, Porto, Portugal Author Marengo, Alessia Department of Drug Sciences, Universita`di P´avia, C. So strada Nuova 65, 27100, Pavia, Italy Author Dethoup, Tida Department of Plant Pathology, Faculty of Agriculture, Kasetsart University, Bangkok, 10240, Thailand Author Pereira, A. J. * & ICBAS-Instituto de Ciˆencias Biom´edicas Abel Salazar, Rua de Jorge Viterbo Ferreira, 228, 4050 - 313, Porto, Portugal & * & Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leix ˜ oes, Av. General Norton de Matos s / n, 4450 - 208, Author Gales, Luís * & ICBAS-Instituto de Ciˆencias Biom´edicas Abel Salazar, Rua de Jorge Viterbo Ferreira, 228, 4050 - 313, Porto, Portugal & Instituto de Biologia Molecular e Celular (i 3 S-IBMC), Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050 - 313, Porto, Portugal Author Freitas-Silva, Joana * & ICBAS-Instituto de Ciˆencias Biom´edicas Abel Salazar, Rua de Jorge Viterbo Ferreira, 228, 4050 - 313, Porto, Portugal & * & Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leix ˜ oes, Av. General Norton de Matos s / n, 4450 - 208, Matosinhos, Portugal Author Costa, Paulo M. * & ICBAS-Instituto de Ciˆencias Biom´edicas Abel Salazar, Rua de Jorge Viterbo Ferreira, 228, 4050 - 313, Porto, Portugal & * & Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leix ˜ oes, Av. General Norton de Matos s / n, 4450 - 208, Matosinhos, Portugal Author Mistry, Sharad Department of Chemistry, University of Leicester, University Road, Leicester, LE 7 RH, UK Author Silva, Artur M. S. Departamento de Química & QOPNA, Universidade de Aveiro, 3810 - 193, Aveiro, Portugal Author Kijjoa, Anake * & ICBAS-Instituto de Ciˆencias Biom´edicas Abel Salazar, Rua de Jorge Viterbo Ferreira, 228, 4050 - 313, Porto, Portugal & * & Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leix ˜ oes, Av. General Norton de Matos s / n, 4450 - 208, Matosinhos, Portugal text Phytochemistry 2021 112575 2021-01-31 181 1 15 http://dx.doi.org/10.1016/j.phytochem.2020.112575 journal article 10.1016/j.phytochem.2020.112575 1873-3700 8290910

Table 1 1 H and 13 C NMR (CDCl, 300 and 75 MHz) and HMBC assignment for 3.

Position	δC, type	δH, (J in Hz)	COSY	HMBC
1/1’ (M, R,	171.60,	–
R)	CO
1/1’ (P, R,	171.56,	–
R)	CO
3/3′	76.6, CH	4.76, m	H-4/4′ Me-
			3, 3′
4/4′	34.7, CH2	3.00, m	H-4/4′, 5/	3/3′, 4a/4’a, 5/5′,
			5′	10a/10’a
4a/4’a	132.9, C	–
5/5′	116.1, CH	6.96, s	H-4/4′	4/4′, 5a/5’a, 6, 6′, 9a/
				9’a, 10a, 10’a
5a/5’a	140.1, C	–
6/6′	98.1, CH	6.71, s		5/5′, 7, 7′, 8/8′, 9a/9’a
7/7′	161.4, C	–
8/8′	108.1, C	–
9/9′	155.4, C	–
9a/9’a	108.5, C	–
10/10′	162.8; C	–
10a/10’a	99.3, C	–
Me-3/3′	20.8, CH3	1.56, d (6.3)		3/3′, 4/4′
OMe-3/3′	55.9, CH3	3.845, s/
		3.843, s
OH-9/9′	–	9.708,		8/8′, 9/9′, 9a/9’a
		d (1.1)
		9.701,
		d (1.1)
OH-10/10′	–	13.806,		8/8′, 10/10′, 10a/10’a
		d (1.1)
		13.803,
		d (1.1)