Kalihiacyloxyamides A-H, α-acyloxy amide substituted kalihinane diterpenes isolated from the sponge Acanthella cavernosa collected in the South China Sea Author Wang, Zhe , Yueying Li &, Di Zhang &, Huiyue Hou &, Li Xiao &, & * & Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People’s Republic of &, Yueying Li &, Di Zhang &, Huiyue Hou &, Li Xiao &, & * & Laboratory of Marine Drugs and Biological Products, National Laboratory for Marine Science and Technology, Qingdao 266235, People’s Republic of China &, Yueying Li &, Xiao Han Author Li, Yueying Author Han, Xiao Author Zhang, Di Author Hou, Huiyue Author Xiao, Li Author Li, Guoqiang text Phytochemistry 2023 113512 2023-02-28 206 1 8 http://dx.doi.org/10.1016/j.phytochem.2022.113512 journal article 10.1016/j.phytochem.2022.113512 1873-3700 8194523

Table 2 1 H NMR data of compounds 5–8 in CDCl (400 MHz, δ in ppm, J in Hz). 3

No.	5	6	7 b	8 a
a Data for s- trans isomer. b Data for s- cis isomer.
1	1.70, m	1.66, m	2.33, m	2.36, m
2	1.38, m; 1.31, m	1.40, m; 1.33,	1.77, m; 1.53,	1.55, m
		m	m
3	1.73, m; 1.48, m	1.76, m; 1.49,	1.95, m	2.05, m; 2.01,
		m		m
5	4.52, brs	4.59, brs	5.70, brs	5.73, brs
6	2.04, m	2.02, m	2.27, m	2.26, m
7	1.63, m	1.75, m	1.51, m	1.50, m
8a	1.58, m	1.66, m	1.64, m	1.45, m
8 b	0.95, m	0.95, m	1.50, m	1.29, m
9	1.99, m; 1.56, m	2.06, m; 1.48,	1.60, m	1.54, m
		m
12	1.60, m; 1.51, m	1.95, m; 1.30,	1.74, m; 1.52,	1.65, m
		m	m
13	2.05, m; 2.01, m	2.35, m; 1.95,	1.90, m; 1.70,	1.86, m; 1.53,
		m	m	m
14	3.76, dd (12.0,	3.97, dd (3.6,	3.89, m	3.76, t (7.2)
	4.8)	3.6)
16	1.34, s	1.35, s	1.36, s	1.19, s
17	1.35, s	1.35, s	1.31, s	1.31, s
18	1.16, s	1.15, s	1.15, s	1.15, s
19	1.40, s	1.41, s	1.61, s	1.61, s
20	1.13, s	1.19, s	1.55, s	1.48, s
3′	1.57, s	1.57, s	1.57, s	1.61, s
4′	1.58, s	1.58, s	1.53, s	1.61, s
6′	3.62, s	3.63, s	2.16, m	2.18, d (7.2)
7′			2.10, m	2.08, m
8’/ 12′	7.28, m	7.28, m	0.98, d (6.4)	0.98, d (6.4)
9’/ 11′	7.37, m	7.37, m	0.98, d (6.4)	0.98, d (6.4)
10′	7.31, m	7.31, m
CHO			8.09, d (1.6)	8.16, d (12.4)
10-	5.46, brs	5.46, brs	5.12, brs	5.77, brs
NH
15-			6.06, brs	5.86, d (12.4)
NH