Kalihiacyloxyamides A-H, α-acyloxy amide substituted kalihinane diterpenes isolated from the sponge Acanthella cavernosa collected in the South China Sea Author Wang, Zhe , Yueying Li &, Di Zhang &, Huiyue Hou &, Li Xiao &, & * & Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People’s Republic of &, Yueying Li &, Di Zhang &, Huiyue Hou &, Li Xiao &, & * & Laboratory of Marine Drugs and Biological Products, National Laboratory for Marine Science and Technology, Qingdao 266235, People’s Republic of China &, Yueying Li &, Xiao Han Author Li, Yueying Author Han, Xiao Author Zhang, Di Author Hou, Huiyue Author Xiao, Li Author Li, Guoqiang text Phytochemistry 2023 113512 2023-02-28 206 1 8 http://dx.doi.org/10.1016/j.phytochem.2022.113512 journal article 10.1016/j.phytochem.2022.113512 1873-3700 8194523

Table 1 1 H NMR data of compounds 1–4 (400 MHz, δ in ppm, J in Hz).

No.	1 a	1b	2 a	3 a	4 a
a Measured in CDCl. 3 b Measured in CD OD.
1	1.79, m	2.12, m	1.76, m	1.70, m	1.68, m
2	1.55, m	1.53, m	1.56, m	1.51, m	1.51, m
3	1.82, m;	1.69, m;	1.82, m;	1.79, m;	1.79, m;
	1.54, m	1.56, m	1.55, m	1.56, m	1.57, m
5	4.57, brs	4.59, brs	4.63, brs	4.56, brs	4.63, brs
6	2.11, m	2.19, m	2.12, m	2.11, m	2.14, m
7	1.67, m	1.63, m	1.78, m	1.65, m	1.77, m
8a	1.62, m	1.67, m	1.71, m	1.63, m	1.71, m
8 b	1.02, m	1.11, m	1.02, m	1.03, m	1.03, m
9	2.28, m;	1.97, m	2.32, m;	2.29, m;	2.33, m;
	1.63, m		1.60, m	1.57, m	1.57, m
12	1.62, m;	1.68, m;	1.95, m;	1.61, m;	1.95, m;
	1.53, m	1.58, m	1.30, m	1.53, m	1.32, m
13	2.07, m;	2.14, m;	2.36, m;	2.07, m;	2.37, m;
	2.01, m	1.99, m	1.95, m	2.01, m	1.95, m
14	3.76, dd	3.80, dd	3.97, dd	3.75, dd	3.98, dd
	(12.0, 4.8)	(12.4, 4.4)	(3.6, 3.6)	(12.0, 4.8)	(3.2, 3.2)
16	1.35, s	1.32, s	1.35, s	1.34, s	1.36, s
17	1.35, s	1.39, s	1.34, s	1.34, s	1.34, s
18	1.19, s	1.25, s	1.17, s	1.19, s	1.18, s
19	1.41, s	1.34, s	1.40, s	1.40, s	1.40, s
20	1.33, s	1.25, s	1.35, s	1.32, s	1.34, s
3′	1.42, s	1.31, s	1.42, s	1.58, s	1.59, s
4′	1.42, s	1.32, s	1.42, s	1.59, s	1.59, s
6′				2.19, d (8.0)	2.20,
					d (7.6)
7′				2.08, m	2.09, m
8′				0.98, d (6.8)	0.99,
					d (6.8)
9′				0.98, d (6.8)	0.99,
					d (6.8)
NH	6.50, brs	7.10, brs	6.55, brs	5.75, brs	5.80, brs