13,13 a-seco-protoberberines from the tubers of Corydalis yanhusuo and their anti-inflammatory activity Author Xia, Gui-Yang , Dong-Jie Fang &, Huan Xia &, Ya-Nan Wang & **, Sheng Lin & * & Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China &, Dong-Jie Fang &, Ling-Yan Wang Author Fang, Dong-Jie Author Wang, Ling-Yan Author Xia, Huan Author Wang, Ya-Nan Author Shang, Hong-Cai Author Lin, Sheng text Phytochemistry 2022 113023 2022-02-28 194 113023 113023 http://dx.doi.org/10.1016/j.phytochem.2021.113023 journal article 10.1016/j.phytochem.2021.113023 1873-3700 8160555

Table 3 The effects of compounds 1–21 on anti-inflammatory activity.

Compounds	IC50 (μ M)	Compounds	IC50 (μ M)
(þ)-1	> 40	10	> 40
()-1	> 40	11	> 40
1	> 40	12	> 40
(þ)-2	> 40	13	> 40
()-2	> 40	14	> 40
2	> 40	15	> 40
3	12.85 ± 1.41	16	> 40
4	2.25 ± 1.32	17	> 40
5	19.17 ± 4.94	18	> 40
6	25.55 ± 1.40	19	> 40
7	> 40	20	> 40
8	> 40	21	> 40
9	> 40	Indomethacin	34.91 ± 3.04