Insight into tetrahydrofuran lignans from Isatis indigotica fortune with neuroprotective and acetylcholinesterase inhibitor activity
Author
Xi, Yu-Fei
, Ming Bai &, Xin Zhang &, Zi-Lin Hou &, Bin Lin &, Li-Li Lou & *, &, Xiao-Xiao Huang & ** & Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province; Engineering Research Center of Natural &, Ming Bai &, Xin Zhang
Author
Bai, Ming
Author
Zhang, Xin
Author
Hou, Zi-Lin
Author
Lin, Bin
Author
Yao, Guo-Dong
Author
Lou, Li-Li
Author
Wang, Xiao-Bo
Author
Song, Shao-Jiang
Author
Huang, Xiao-Xiao
text
Phytochemistry
2023
113609
2023-04-30
208
113609
113609
http://dx.doi.org/10.1016/j.phytochem.2023.113609
journal article
10.1016/j.phytochem.2023.113609
1873-3700
8160720
Table 2 Inhibitory effects of compounds on AChE (IC 50, μ M).| Compound | AChE inhibitory | Compound | AChE inhibitory |
|---|
| a Positive control. |
| 1a | 10.37 | 4 | 30.59 |
|---|
| 1b | 0.67 | 5 | 37.17 |
|---|
| 2 | 17.45 | 6 | 1.26 |
|---|
| 3a | 29.12 | 7 | 1.01 |
|---|
| 3b | 20.66 | Donepezil a | 0.82 |
|---|